The Effects of Jiang-Zhi-Ning and Its Main Components on Cholesterol Metabolism

Table 5

The effects of chrysophanol treatment on cholesterol metabolism in liver cells (mRNA analysis).

Treatment	LDL-R	HMG-CoAR	CYP7A1	ACAT2
No chrysophanol	0.42±0.07	0.41±0.11	0.28±0.07	0.64±0.15
Chrysophanol: low dose	0.62±0.04 *	0.54±0.19 *	0.31±0.12	0.42±0.16 **
Chrysophanol: medium dose	0.75±0.03 **	0.72±0.14 **	0.33±0.09 *	0.37±0.18 **
Chrysophanol: high dose	0.88±0.09 **	0.81±0.22 **	0.37±0.14 **	0.30±0.07 **
Atorvastatin	0.93±0.07 **	0.86±0.18 **	0.49±0.13 *	0.31±0.13 **

Note: comparison with no-drug control group, *𝑃<0.05, **𝑃<0.01.