The Effects of Jiang-Zhi-Ning and Its Main Components on Cholesterol Metabolism

Table 4

The effects of hyperin on cholesterol metabolism in liver cells (mRNA analysis).

Treatment	LDL-R	HMG-CoAR	CYP7A1	ACAT2
No hyperin	1	1	1	1
Hyperin: low dose	1.64±0.27 *	2.18±0.19 **	1.21±0.18 *	1.03±0.21
Hyperin: medium dose	2.82±0.36 **	3.29±0.31 **	1.57±0.22 **	0.65±0.36 **
Hyperin: high dose	2.66±0.24 **	2.87±0.25 **	1.06±0.19	0.61±0.29 **
Atorvastatin	5.82±0.27 **	6.48±0.29 **	1.29±0.45 **	0.49±0.38 **

Note: comparison with no-drug control group, *𝑃<0.05, **𝑃<0.01.