Evidence-Based Complementary and Alternative Medicine

Research Article

Inhibitory Activities of Cudrania tricuspidata Leaves on Pancreatic Lipase In Vitro and Lipolysis In Vivo

Table 1

Lipase inhibitory activities of extracts from herbs.
Scientific nameFamilyPart usedConc. (μg/mL)Inhibition (%)aIC50 (μg/mL)
   2.5  
Solidago  serotina CompositaeWhole plant5 5.16
   7.5  
   5  
Acer  mono AceraceaeBranch, leaf7.5 7.7
   10  
   5  
Cudrania  tricuspidata MoraceaeLeaf7.5 9.91
   10  
   10  
Kalopanax  pictus AraliaceaeBark50 10.51
   100  
   5  
Cudrania  tricuspidata MoraceaeBranch, stem10 13.8
   50  
   10  
Oenothera  odorata OnagraceaeWhole plant50 23.34
   100  
   10  
Platycarya  strobilacea JuglandaceaeBranch, stem50 25.51
   100  
   10  
Actinidia  arguta ActinidiaceaeFruit50 26.7
   100  
   10  
Tilia  amurensis TiliaceaeBranch, leaf50 28.5
   100  
   10  
Actinidia  arguta ActinidiaceaeStem50 28.51
   100  
   20  
Euscaphis  japonica StaphyleaceaeBranch30 28.62
   40  
   10  
Actinidia  arguta ActinidiaceaeRoot50 31.34
   100  
   10  
Carpinus  cordata BetulaceaeBranch, stem50 31.39
   100  
   10  
Rhus  sylvestris AnacardiaceaeBranch, leaf50 32.14
   100
   10  
Celtis  sinensis UlmaceaeBranch, stem50 35.89
   100  
   10  
Prunus  serrulata RosaceaeBranch, leaf50 42.55
   100  
   10  
Potentilla  fragarioides RosaceaeWhole plant50 42.58
   100  
   10  
Tilia  mandshurica TiliaceaeFlower, leaf50 48.21
   100  
   10  
Actinidia  arguta ActinidiaceaeStem, leaf, fruit50 54.09
   100  
   10  
Hypericum  ascyron HypericaceaeWhole plant50 56.12
   100  
   10  
Rhus  chinensis AnacardiaceaeBranch, leaf50 56.9
   100  
   10  
Picrasma  quassioides SimaroubaceaeBranch, stem50 60.47
   100  
   10  
Prunus  persica RosaceaeBranch, leaf50 62.12
   100  
   10  
Actinidia  arguta ActinidiaceaeRoot50 69.17
   100  
   10  
Spiraea  pubescens RosaceaeBranch, leaf, flower50 74.62
   100  
   10  
Tilia  mandshurica TiliaceaeBranch, stem50 79.67
   100  
   10  
Acer  ginnala AceraceaeBranch, leaf50 82.29
   100  
   10  
Elsholtzia  splendens LabiataeRoot50 83.98
   100
   10  
Staphylea  bumalda StaphyleaceaeBranch, leaf50 84.28
   100  
   80  
Pinus  densiflora PinaceaeStem90 87.58
   100  
   10  
Machilus  thunbergii LauraceaeLeaf, branch50 90.9
   100  
   10  
Deutzia  glabrata SaxifragaceaeBranch, leaf, flower50 91.09
   100  
   10  
Indigofera  kirilowii LeguminosaeBranch, leaf, flower50 94.98
   100  
Opuntia  ficus-indica OpuntiacaeStem100 >100
Hibiscus  syriacus MalvaceaeRoot100 >100
Actinidia  arguta ActinidiaceaeBark100 >100
Euonymus  oxyphyllus CelastraceaeBranch100 >100
Eucommia  ulmoides EucommiaceaeBranch, leaf100 >100
Asarum  sieboldii AristolochiacRoot100 >100
Bupleurum  longeradiatum UmbelliferaeWhole plant100 >100
Plantago  asiatica PlantaginaceaRoot100 >100
Alisma  plantago-aquatica AlismataceaeRoot100 >100
Duchesnea  chrysantha RosaceaeWhole plant100 >100
Cuscuta  japonica ConvolvulaceaeWhole plant100 >100
Clematis  apiifolia RanunculaceaeStem, leaf, flower100 >100
Prunus  serrulata RosaceaeBranch100 >100
Colocasia  antiquorum AraceaeAerial part100 >100
Lespedeza  cuneata LeguminosaeAerial part100 >100
Lespedeza  cuneata LeguminosaeRoot100 >100
Mallotus  japonicas EuphorbiaceaeAerial part100 >100
Alisma  canaliculatum AlismataceaeAerial part100 >100
Alisma  canaliculatum AlismataceaeRoot100 >100
Magnolia  denudata MagnoliaceaeFlowers100 >100
Scopolia  japonica SolanaceaeStem, leaf100 >100
Scopolia  japonica SolanaceaeRoot100 >100
Chloranthus  japonicus ChloranthaceaeWhole plant100 >100
Barbarea  orthoceras CruciferaeWhole plant100 >100
Caulophyllum  robustum BerberidaceaeStem, leaf100 >100
Caulophyllum  robustum BerberidaceaeRoot100 >100
Carduus  crispus CompositaeStem, leaf100 >100
Carduus  crispus CompositaeFlower100 >100
Styrax  japonica StyracaceaeFlower100 >100
Cornus  controversa CornaceaeBranch, leaf100 >100
Cornus  controversa CornaceaeFlower100 >100
Magnolia  sieboldii MagnoliaceaeBranch, leaf100 >100
Magnolia  sieboldii MagnoliaceaeFlower100 >100
Prunus  persica RosaceaeFruit100 >100
Rhamnus  yoshinoi RhamnaceaeBranch, leaf100 >100
Erigeron  annuus CompositaeWhole plant100 >100
Styrax  japonica StyracaceaeBranch, leaf100 >100
Quercus  aliena FagaceaeBranch, leaf100 >100
Callicarpa  japonica VerbenaceaeBranch, leaf100 >100
Ligustrum  obtusifolium OleaceaeBranch, leaf100 >100
Lindera  obtusiloba LauraceaeBranch, leaf100 >100
Lespedeza  bicolor LeguminosaeBranch, leaf100 >100
Carpinus  laxiflora BetulaceaeBranch, leaf100 >100
Machilus  thunbergii LauraceaeBark100 >100
Hedera  rhombea AraliaceaeWhole plant100 >100
Arenaria  serpyllifolia CaryophyllaceaeWhole plant100 >100
Paulownia  coreana PaulowniaceaeFlower100 >100
Thlaspi  arvense BrassicaceaeWhole plant100 >100
Vicia  villosa LeguminosaeWhole plant100 >100
Descurainia  pinnata BrassicaceaeWhole plant100 >100
Ribes  fasciculatum SaxifragaceaeBranch, leaf, fruit100 >100
Corydalis  speciosa FumariaceaeWhole plant100 >100
Clematis  fusca RanunculaceaeWhole plant100 >100
Deutzia  parviflora SaxifragaceaeBranch, leaf, stem, flower100 >100
Rosa  multiflora RosaceaeBranch, leaf, stem, flower100 >100
Parthenocissus  tricuspidata VitaceaeLeaf, stem100 >100
Chelidonium  majus PapaveraceaeWhole plant100 >100
Platycarya  stobilacea JuglandaceaeLeaf100 >100
Platycarya  stobilacea JuglandaceaeFlower100 >100
Carpinus  cordata BetulaceaeLeaf100 >100
Celtis  sinensis UlmaceaeLeaf100 >100
Orixa  japonica RutaceaeLeaf100 >100
Orixa  japonica RutaceaeBranch, stem100 >100
Orixa  japonica RutaceaeFruit100 >100
Picrasma  quassioides SimaroubaceaeLeaf100 >100
Picrasma  quassioides SimaroubaceaeFruit100 >100
Tilia  mandshurica TiliaceaeLeaf100 >100
Aralia  cordata AraliaceaeWhole plant100 >100
Viburnum  sargentii CaprifoliaceaeBranch, leaf100 >100
Polygonatum  odoratum LiliaceaeRoot　 　100 >100
Astragalus  membranaceus LeguminosaeRoot　100 >100
Pleuropterus  multiflorus PolygonaceaeRoot　100 >100
Torilis  japonica UmbelliferaeFruit　100 >100
Phaseolus  angularis LeguminosaeFruit　100 >100
Phaseolus  radiates LeguminosaeFruit　100 >100
Artemisia  scoparia CompositaeAerial part　100 >100
Solanum  tuberosum SolanaceaeTuber100 >100
Brassica  juncea CruciferaeLeaf　100 >100
Arctium  lappa CompositaeRoot100 >100
Cucumis  sativus CucurbitaceaeFruit　100 >100
Diospyros  kaki EbenaceaeFruit　 　100 >100
Artemisia  princeps CompositaeAerial part　100 >100
   0.0005  
Orlistat (positive control)  0.005 0.036 (0.073 μM)
   0.05  
aResults are the mean ± SD ( ).