Research Article

Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response

Figure 5

Effect of thymol on ear edema (a) and myeloperoxidase activity (MPO) (b) in ear tissues from mice. The animals ( ) were treated topically with indomethacin (Indo) or dexamethasone (Dex) 1 h before croton oil application (10  L/ear). The group treated with thymol did not received the croton oil. Dex (0.1 mg/ear) and Indo (0.5 mg/ear) were used as anti-inflammatory drugs (positive control). The right ears received only the vehicle. Data are mean ± SEM weight of the ears (a) or MPO activity (b), 4 hours after application of croton oil or thymol. # , compared to the control group (croton oil) (ANOVA, Tukey’s test).
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(a)
657026.fig.005b
(b)