Effects of Thymol and Carvacrol, Constituents of Thymus vulgaris L. Essential Oil, on the Inflammatory Response
Figure 4
Effect of CVL on ear edema (a) and myeloperoxidase activity (MPO) (b) induced by croton oil in ear tissues from mice. The animals () were treated topically with carvacrol, indomethacin (Indo), or dexamethasone (Dex) 1 h before croton oil application (10 L/ear). Dex (0.1 mg/ear) or Indo (0.5 mg/ear) were used as anti-inflammatory drugs (positive control). The right ears received only the vehicle (Basal). Data are mean ± SEM weight of the ears (a) or MPO activity (b), 4 hours after application of croton oil, #, compared to the control group (croton oil) (ANOVA, Tukey’s test).