Ferulsinaic Acid Modulates SOD, GSH, and Antioxidant Enzymes in Diabetic Kidney
Table 2
Oxidant/antioxidant parameters as well as concentration of AGEs, CML, and IL-6 of rat kidney.
Normal control
DN
DN + MF
DN + FA1
DN + FA2
DN + FA3
SOD, U/mg protein
GSH, nmol/mg protein
MDA, nmol/g protein
AGEs, AU
CML, ng/mg protein
IL-6, ng/mg protein
Data are expressed as the means ± SD. DN: diabetes group; FA1, FA2, FA3, and MF: diabetic rats treated with low dose (5 mg/kg) of FA (DN + FA1), middle dose (50 mg/kg) of FA (DN + FA2), high dose (500 mg/kg) of FA (DN + FA3), and (125 mg/kg) of metformin (DN + MF), respectively. Each group consisted of 10 animals. versus normal control group, versus DN group, versus DN + FA1 group, versus DN + FA2 group.