Research Article

Ecklonia cava Inhibits Glucose Absorption and Stimulates Insulin Secretion in Streptozotocin-Induced Diabetic Mice

Table 1

Effect of Ecklonia cava (EC) on blood glucose regulation.

NCNEDCDE

Body weight gain (g)7.8 ± 0.9a8.4 ± 0.6a−5.9 ± 0.7b−2.1 ± 0.4c
Glucose uptake1357 ± 28a304 ± 17a499 ± 33b392 ± 22a,c
SGLT1 expression21.00 ± 0.21a0.83 ± 0.22a2.61 ± 0.34b1.72 ± 0.20c
Blood glucose (mg/dL)112 ± 10a109 ± 1a395 ± 13b240 ± 19c
Plasma insulin (ng/mL)1.28± 0.03a1.25± 0.03a0.50 ± 0.01b0.96 ± 0.03c

Values are means ± SE of 10 mice in each group. NC: normal control mice; NE: normal mice supplied with EC powder (3%). DC: STZ-mice; DE: STZ-mice supplied with EC. 1Na+-dependent glucose uptake by BBMV was expressed as fluorescence intensity. 2Relative SGLT1 protein expression.
Different superscript letter means significantly different at .