Research Article

An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study

Table 5

Effect of GutGard on the individual symptoms scores.

ParameterGroups ( )Day 15Day 30
Change in scoreEffect sizeChange in scoreEffect size

Upper abdominal fullnessPlacebo−0.520.393−0.880.665
GutGard−1.725.186−2.286.875
Upper abdominal painPlacebo−0.040.084−0.160.336
GutGard−1.241.127−1.881.709
 BelchingPlacebo−0.760.734−0.960.927
GutGard−1.162.352−1.402.838
 BloatingPlacebo−0.80.755−1.081.019
GutGard−1.041.733−1.362.267
 Early satietyPlacebo−0.880.848−1.041.002
GutGard−0.520.770−0.721.065
 NauseaPlacebo−0.160.225−0.280.393
GutGard−0.561.065−0.921.749
 VomitingPlacebo−0.160.210−0.320.419
GutGard−0.681.133−0.801.333
 RegurgitationPlacebo−0.280.211−0.800.603
GutGard−1.521.675−1.842.028
 HeartburnPlacebo−0.840.899−1.441.541
GutGard−1.521.568−2.122.187
 Loss of appetitePlacebo−0.640.492−1.280.985
GutGard−1.360.905−1.881.252