Research Article

An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study

Table 1

Inclusion and exclusion criteria.

Inclusion criteria
(i) Diagnosis of functional dyspepsia/nonulcer dyspepsia by fulfilling Rome-III criteria
(ii) Should be suffering with at least 4 or more symptoms mentioned below and with total symptom score of 20 or more based on 7-point Likert scale
 (a) Upper abdominal fullness
 (b) Upper abdominal pain
 (c) Belching
 (d) Bloating
 (e) Early satiety
 (f) Nausea
 (g) Vomiting
 (h) Regurgitation
 (i) Heartburn
 (j) Loss of appetite
Exclusion criteria
(i) Age less than 18 years or over 65 years
(ii) Advanced chronic illness that would impair follow-up or monitoring
(iii) Pregnancy or breast feeding
(iv) Previous surgery for ulcers
(v) Subjects with previous history of gastroesophageal reflux
(vi) Subjects with concomitant symptoms of the irritable bowel syndrome
(vii) Drug and alcohol abuse
(viii) Mental illness or dementia