Research Article
An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study
Table 1
Inclusion and exclusion criteria.
| Inclusion criteria | | (i) Diagnosis of functional dyspepsia/nonulcer dyspepsia by fulfilling Rome-III criteria | | (ii) Should be suffering with at least 4 or more symptoms mentioned below and with total symptom score of 20 or more based on 7-point Likert scale | | (a) Upper abdominal fullness | | (b) Upper abdominal pain | | (c) Belching | | (d) Bloating | | (e) Early satiety | | (f) Nausea | | (g) Vomiting | | (h) Regurgitation | | (i) Heartburn | | (j) Loss of appetite | | Exclusion criteria | | (i) Age less than 18 years or over 65 years | | (ii) Advanced chronic illness that would impair follow-up or monitoring | | (iii) Pregnancy or breast feeding | | (iv) Previous surgery for ulcers | | (v) Subjects with previous history of gastroesophageal reflux | | (vi) Subjects with concomitant symptoms of the irritable bowel syndrome | | (vii) Drug and alcohol abuse | | (viii) Mental illness or dementia | |
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