Evidence-Based Complementary and Alternative Medicine / 2011 / Article / Fig 1

Research Article

Neuroprotection by the Traditional Chinese Medicine, Tao-Hong-Si-Wu-Tang, against Middle Cerebral Artery Occlusion-Induced Cerebral Ischemia in Rats

Figure 1

Effects of Tao-Hong-Si-Wu-Tang (THSWT) in middle cerebral artery occlusion-(MCAO-) induced focal cerebral ischemia in rats. (a) Coronal sections of 2,3,5-triphenyltetrazolium-(TTC-) stained brains, (b) dose-response effect of THSWT, and (c) the infarct area at various distances from the frontal pole 24 h after MACO-reperfusion rats. Cerebral infarction in sham-operated (sham) or MACO-reperfusion rats is from a representative animal that received the solvent (distilled water) or THSWT (0.7 and 1.4 g  ) orally for 14 days. (a) TTC-stained brains and (b) infarct volumes were calculated as described in “Methods”, and data are presented as the infarct volume for each animal in the group as well as the ( ). , compared to the sham-operated group. (c) Forebrain profiles of the infarct area at various distances from the frontal pole as described in “Methods”. Each point (○, solvent-treated group; Δ, THSWT 0.7 g  -treated group) and vertical bar represent the means   S.E.M. ( ). and , compared to the solvent-treated group.

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