Antiproliferative Activity of Cinnamomum cassia Constituents and Effects of Pifithrin-Alpha on Their Apoptotic Signaling Pathways in Hep G2 Cells

Table 1

Effects of Cin-induced apoptosis on human Hep G2 cells.

Cin treatment (𝜇M)	Apoptotic cells (%)
	0 h	6 h	12 h	24 h
0	0.10 ± 0.00^c	0.10 ± 0.08^d	0.10 ± 0.08^d	0.13 ± 0.05^d
1	0.50 ± 0.16^c	8.25 ± 0.94^c	17.07 ± 0.74^c	41.13 ± 0.74^c
10	5.00 ± 0.82^b	13.20 ± 0.80^b	45.96 ± 0.23^b	50.10 ± 0.70^b
30	16.98 ± 0.14^a	38.67 ± 2.49^a	60.32 ± 0.50^a	70.73 ± 3.03^a

After treatment, cell numbers were estimated by the XTT assay. Data are presented as means ± SD of three independent experiments. Values within the column with different superscript letters were significant at P < .05.