Comparative Analysis of Gelsemine and Gelsemium sempervirens Activity on Neurosteroid Allopregnanolone Formation in the Spinal Cord and Limbic System
Figure 6
Effects of gelsemine (a) or G. sempervirens (b) at 5 cH on []3,5-THP production by SC slices in the absence or presence of strychnine ( M), the specific glycine receptor antagonist. The values were obtained from experiments similar to those presented in Figure 1. Results were then expressed as percentages of the amount of []3,5-THP formed in the control group. Each value is the mean (SEM) of four independent experiments. as compared to gelsemine; , as compared to G. sempervirens (ANOVA followed by Bonferroni's test). NS represents not statistically different.
