The Efficacy of Dandelion Root Extract in Inducing Apoptosis in Drug-Resistant Human Melanoma Cells

Figure 3

Caspase-8 activity in DRE-treated A375 cells. A375 cells were treated at 2.5 mg/mL for the indicated periods of time. Cells were collected and incubated with caspase-8 IETD-AFC substrate for an hour before being read on a spectrofluorometer as described in Section 2. Statistical analysis was performed using the GraphPad Prism 5.0; *denotes a P-value <.05; **denotes a P-value <.01.