The metastatic spread of malignant melanoma (MM) cells is a leading cause of death from skin cancers worldwide. Beyond diagnosing and treating early primary MM, searching for and eradicating MM metastases represent the main endeavour clinicians make for these patients. Potential topics include, but are not limited to:

• Clinical and biological clues for MM progression
• Staging of metastatic MM
• Diagnostic functional imaging
• Immunohistochemistry and molecular studies
• MM stem cells and MM circulating cells
• Mechanisms of MM metastasis
• The 4 routes of MM metastases (intravascular, intramural, perivascular, and interstitial)
• MM metastases and the tumoral growth fraction
• Prognosis of metastatic MM
• Therapy of metastatic MM including anti-MM vaccines

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