Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA-IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross-Sectional Study
Table 1
General characteristics and clinical, anthropometric, metabolic, and inflammatory profiles by Burke’s classification in obese children.
Burke’s classification scale
0 (N=21, 22.10%)
1 (N=30, 31.57%)
2 (N=17, 17.89%)
3 (N=12, 12.63%)
4 (N=15, 15.78%)
value
Age (years)
9.52 ±1.6
9.0 ±1.8
8.76 ±2.01
9.33 ±1.92
9.33 ±1.44
0.74
Male (%)
19.67
37.7
19.67
9.84
13.12
0.33
Female (%)
26.47
20.59
14.71
17.64
20.59
FHOB (%)
No
21.57
39.22
13.73
11.76
13.73
0.44
Yes
26.09
21.74
21.74
13.04
17.39
FHT2D (%)
No
22.09
30.23
11.63
19.77
16.28
0.43
Yes
33.33
33.33
8.33
16.67
8.33
BMI (kg/m2)
22.7 ± 2.8
23.9 ± 3
23.6 ± 3.3
25.3 ± 2.7
24.9 ± 2.4
0.76
Waist circumference (cm)
76.1 ± 8.2
80.3 ± 8.1
78.2 ± 11.4
83.0 ±9
80.9 ± 8
0.49
SBP (mmHg)
102.6 ± 9.6
102.8 ± 11.3
103.0 ± 12.6
109.6 ± 12.8
101.1 ± 9.3
0.63
DBP (mmHg)
67.5 ± 7.5
69.6 ± 9.5
68.1 ± 17.5
72.1 ±9.2
71.9 ± 8
0.001
Glucose (mg/dL)
87.5 ± 9.6
86.9 ± 6.3
86.4 ± 7.5
86.9 ± 8.4
83.4 ± 6.9
0.32
Insulin (µU/ml)
10.2 ± 5.6
9.0 ± 5.2
11.1 ± 6.9
13.9 ± 8.3
12.6 ± 5.7
0.15
HOMA-IR
2.1 ± 1.2
1.9 ± 1.2
2.4 ± 1.7
3.1 ± 2
2.7 ± 1.3
0.3
Total cholesterol (mg/dL)
139.0 ± 27
152.9 ± 35.7
136.4 ± 34.3
172.7 ± 41.3
153.8 ± 27.8
0.46
Triglycerides (mg/dL)
97.2 ± 38.9
102.7 ± 33.2
112.8 ± 49.4
149.7 ± 68.7
117.2 ± 49.3
0.02
HDL-C (mg/dL)
41.9 ± 9.9
45.4 ± 10.4
42.0 ± 9.2
42.1 ± 10.9
40.7 ± 7.8
0.8
LDL-C (mg/dL)
94.8 ± 21.2
105.3 ± 29
90.8 ± 25.3
122.9 ± 32.7
106.8 ± 24
0.47
Adiponectin (µg/mL)
12 ± 1.8
12.2 ± 2.2
12.4 ± 1.4
12.1 ± 1
12.1 ± 1.2
0.02
Leptin (ng/mL)
36.6 ± 12.2
38.8 ± 15.3
39.18 ± 12.3
37.7 ± 8.7
41.4 ± 9.4
0.18
DBP: Diastolic blood pressure; SBP: systolic blood pressure; BMI: body mass index; FHOB: family history of obesity; FHT2D: family history of type 2 diabetes. Results are shown as mean ± standard deviation. indicates a statistical significance.