Research Article

Severe Quantitative Scale of Acanthosis Nigricans in Neck is Associated with Abdominal Obesity, HOMA-IR, and Hyperlipidemia in Obese Children from Mexico City: A Cross-Sectional Study

Table 1

General characteristics and clinical, anthropometric, metabolic, and inflammatory profiles by Burke’s classification in obese children.

Burke’s classification scale
0 (N=21, 22.10%)1 (N=30, 31.57%)2 (N=17, 17.89%)3 (N=12, 12.63%)4 (N=15, 15.78%) value

Age (years)9.52 ±1.69.0 ±1.88.76 ±2.019.33 ±1.929.33 ±1.440.74
Male (%)19.6737.719.679.8413.120.33
Female (%)26.4720.5914.7117.6420.59

FHOB (%)
 No21.5739.2213.7311.7613.730.44
 Yes26.0921.7421.7413.0417.39

FHT2D (%)
 No22.0930.2311.6319.7716.280.43
 Yes33.3333.338.3316.678.33

BMI (kg/m2)22.7 ± 2.823.9 ± 323.6 ± 3.325.3 ± 2.724.9 ± 2.40.76
Waist circumference (cm)76.1 ± 8.280.3 ± 8.178.2 ± 11.483.0 ±980.9 ± 80.49
SBP (mmHg)102.6 ± 9.6102.8 ± 11.3103.0 ± 12.6109.6 ± 12.8101.1 ± 9.30.63
DBP (mmHg)67.5 ± 7.569.6 ± 9.568.1 ± 17.572.1 ±9.271.9 ± 80.001
Glucose (mg/dL)87.5 ± 9.686.9 ± 6.386.4 ± 7.586.9 ± 8.483.4 ± 6.90.32
Insulin (µU/ml)10.2 ± 5.69.0 ± 5.211.1 ± 6.913.9 ± 8.312.6 ± 5.70.15
HOMA-IR2.1 ± 1.21.9 ± 1.22.4 ± 1.73.1 ± 22.7 ± 1.30.3
Total cholesterol (mg/dL)139.0 ± 27152.9 ± 35.7136.4 ± 34.3172.7 ± 41.3153.8 ± 27.80.46
Triglycerides (mg/dL)97.2 ± 38.9102.7 ± 33.2112.8 ± 49.4149.7 ± 68.7117.2 ± 49.30.02
HDL-C (mg/dL)41.9 ± 9.945.4 ± 10.442.0 ± 9.242.1 ± 10.940.7 ± 7.80.8
LDL-C (mg/dL)94.8 ± 21.2105.3 ± 2990.8 ± 25.3122.9 ± 32.7106.8 ± 240.47
Adiponectin (µg/mL)12 ± 1.812.2 ± 2.212.4 ± 1.412.1 ± 112.1 ± 1.20.02
Leptin (ng/mL)36.6 ± 12.238.8 ± 15.339.18 ± 12.337.7 ± 8.741.4 ± 9.40.18

DBP: Diastolic blood pressure; SBP: systolic blood pressure; BMI: body mass index; FHOB: family history of obesity; FHT2D: family history of type 2 diabetes. Results are shown as mean ± standard deviation. indicates a statistical significance.