The Association between Adiponectin Single Nucleotide Polymorphisms and Side Effects of Isotretinoin in Acne Patients

Table 5

Genotypes frequencies of tested polymorphisms according to common adverse effects of isotretinoin treatment.

Parameter		rs2241766			value	rs1501299		value
		GG, number (%)	TG, number (%)	TT, number (%)		GG, number (%)	GT, number (%)
Joint pain	Yes	2 (0.9)	43 (19.5)	122 (55.5)	0.708	87 (39.5)	80 (36.4)	0.926
	No	0 (0.0)	13 (5.9)	40 (18.2)		28 (12.7)	25 (11.4)
Mucosal dryness/nose bleed	Yes	1 (0.5)	32 (14.5)	89 (40.5)	0.948	65 (29.5)	57 (25.9)	0.739
	No	1 (0.5)	24 (10.9)	73 (33.2)		50 (22.7)	48 (21.8)
Headache	Yes	0 (0.0)	33 (15.0)	91 (41.4)	0.255	70 (31.8)	54 (24.5)	0.158
	No	2 (100)	23 (41.1)	71 (43.8)		45 (20.5)	51 (23.2)