The Association between Adiponectin Single Nucleotide Polymorphisms and Side Effects of Isotretinoin in Acne Patients
Table 3
Means and standard deviations of biochemical parameters (baseline, after treatment, and percentage of change by treatment) for the genotype of rs2241766.
Parameter
Genotypes
value
TT, mean (SD)
TG/GG, mean (SD)
HDL (mmol/L)
Baseline
1.44 (0.377)
1.42 (0.315)
0.930
After treatment
1.304 (0.310)
1.34 (0.327)
0.553
% change by treatment
−7.4% (14.86)
−4.2% (19.41)
0.129
LDL (mmol/L)
Baseline
2.35 (0.70)
2.32 (0.67)
0.275
After treatment
2.85 (0.75)
2.74 (0.83)
0.570
% change by treatment
2.5% (25.7)
1.9% (20.9)
0.699
TChol (mmol/L)
Baseline
4.22 (0.85)
4.03 (1.08)
0.636
After treatment
4.71 (0.91)
4.57 (1.10)
0.339
% change by treatment
12.8% (14.4)
1.6% (20.4)
0.074
TG (mmol/L)
Baseline
0.99 (0.57)
1.00 (0.66)
0.642
After treatment
1.31 (0.71)
1.27 (0.71)
0.872
% change by treatment
43.3% (58.76)
42.3% (78.0)
0.219
AST (U/I)
Baseline
19.5 (6.60)
17.59 (4.00)
0.118
After treatment
21.84 (7.64)
20.39 (7.77)
0.337
% change by treatment
15.3% (35.0)
16.5% (30.7)
0.664
ALT (U/I)
Baseline
16.25 (8.34)
14.97 (7.63)
0.338
After treatment
17.17 (8.26)
18.20 (14.73)
0.142
% change by treatment
13.2% (46.04)
21.5% (51.88)
0.396
Student’s t-test was used. value is significant at less than 0.05. HDL: high-density lipoprotein. LDL: low-density lipoprotein. TChol: total cholesterol. AST: aspartate aminotransferase. ALT: alanine aminotransferase.
