Marital Status and Survival in Patients Diagnosed with Melanoma

Table 3

Associations between marital status and survival in Florida melanoma patients between 2001 and 2009.

		Unadjusted		Adjusted
		HR (99% CI)	value	HR (99% CI)	value
Marital status	Single (never married)	Reference	Reference	Reference	Reference
	Married	0.78 (0.72–0.85)	<0.001	0.65 (0.57–0.74)	<0.001
	Divorced	0.97 (0.86–1.10)	0.566	0.89 (0.74–1.08)	0.117
	Widowed	1.59 (1.44–1.76)	<0.001	0.87 (0.74–1.01)	0.019
Age at diagnosis		1.04 (1.04–1.04)	<0.001	1.05 (1.04–1.05)	<0.001
Sex	Female	Reference	Reference	Reference	Reference
	Male	1.49 (1.40–1.58)	<0.001	1.33 (1.22–1.46)	<0.001
Insurance status	Insurance	Reference	Reference	Reference	Reference
	No insurance	1.36 (1.16–1.58)	<0.001	1.76 (1.42–2.19)	<0.001
Race	White	Reference	Reference	Reference	Reference
	Black	1.63 (1.21–2.20)	<0.001	1.66 (1.10–2.52)	0.002
	Other	0.83 (0.51–1.35)	0.315	0.99 (0.51–1.93)	0.966
Ethnicity	Non-Hispanic	Reference	Reference	Reference	Reference
	Hispanic	1.29 (1.12–1.49)	<0.001	1.39 (1.13–1.71)	<0.001
Tobacco use	Never	Reference	Reference	Reference	Reference
	Current	1.33 (1.21–1.46)	<0.001	1.461 (1.304–1.638)	<0.001
	Former	1.36 (1.26–1.46)	<0.001	1.14 (1.05–1.25)	<0.001
Histology	Superficial spreading	Reference	Reference	Reference	Reference
	Acral lentiginous	1.38 (1.19–1.60)	<0.001	1.10 (0.91–1.34)	0.182
	Lentigo maligna	2.22 (1.68–2.95)	<0.001	1.30 (0.91–1.86)	0.055
	Nodular	2.75 (2.41–3.14)	<0.001	1.56 (1.33–1.83)	<0.001
	Other	1.54 (1.39–1.71)	<0.001	1.10 (0.97–1.25)	0.046
Staging	Early	Reference	Reference	Reference	Reference
	Late	4.32 (4.05–4.60)	<0.001	3.49 (3.18–3.82)	<0.001
Primary site	Face	Reference	Reference	Reference	Reference
	External ear	1.06 (0.91–1.24)	0.333	0.97 (0.78–1.19)	0.664
	Scalp and neck	1.18 (1.06–1.32)	<0.001	1.09 (0.94–1.26)	0.142
	Trunk	0.80 (0.73–0.87)	<0.001	1.00 (0.89–1.13)	0.989
	Upper limb and shoulder	0.82 (0.75–0.90)	<0.001	0.91 (0.80–1.02)	0.034
	Lower limb and hip	0.75 (0.68–0.83)	<0.001	0.85 (0.74–0.98)	0.004
Geographic area	Northwest	Reference	Reference	Reference	Reference
	Northeast	0.70 (0.60–0.82)	<0.001	0.66 (0.53–0.83)	<0.001
	North central	0.72 (0.59–0.88)	<0.001	0.75 (0.56–0.99)	0.009
	Central west	0.77 (0.68–0.88)	<0.001	0.68 (0.56–0.84)	<0.001
	Central	0.54 (0.47–0.62)	<0.001	0.57 (0.47–0.70)	<0.001
	Central east	0.88 (0.76–1.02)	0.025	0.77 (0.62–0.96)	0.002
	Southeast	0.75 (0.66–0.85)	<0.001	0.68 (0.56–0.83)	<0.001
	Southwest	0.77 (0.67–0.90)	<0.001	0.67 (0.53–0.84)	<0.001

SD = standard deviation; ref = reference; HR = hazard ratio; CI = confidence interval. The races grouped under “others” consist of Micronesian, Chamorro/Chamoru, American Indian, Aleutia, Alaskan Native or Eskimo (includes all indigenous populations of the Western hemisphere), Chinese, Polynesian, Japanese, Tahitian, Filipino, Samoan, Hawaiian, Tongan, Korean, Melanesian, Vietnamese, New Guinean, Laotian, Other Asian, including Asian, not otherwise specified, Hmong, Pacific Islander, Kampuchean, Thai, Asian Indian or Pakistani, Asian Indian, Pakistani, Guamanian, Fiji Islanders, and Oriental, not otherwise specified, as well as unknown races. The histological categories grouped under “others” consist of Malignant Melanoma NOS, Balloon Cell Melanoma, Regressing Melanoma, Meningeal Melanomatosis, Amelanotic Melanoma, Melan Junction Nevus, Melan in Precanc Melanoma, Desmoplastic Melanoma, Mucosal Lentiginous Melan, Melan Giant Pig Nevus, Epithelioid/Spindle Cell Melan, Epithel Cell Melanoma, Spindle Cell Melanoma NOS, Spindle Cell Melanoma type A, Spindle Cell Melanoma type B, and Blue Nevus Malignant.