Disease Markers

Research Article

Evaluation of lncRNA Expression Pattern and Potential Role in Heart Failure Pathology

Table 1

Clinical characteristics of the healthy control and HF patients.


	CT	HF	value

Male/female (/)	18/32	21/29	0.1695
Age (year)			0.1197
BMI (kg/m2)			0.9913
Heart rate (time/minute)			0.1931
SBP (mmHg)			0.1617
DBP (mmHg)			0.3995
Hemoglobin (g/L)			0.0633
LDH (U/L)			0.0173
CK (U/L)			0.8359
CHO (mmol/L)			0.0072
TG (mmol/L)			0.0099
LDL (mmol/L)			0.0337
HDL (mmol/L)			0.515
ApoA (g/L)			0.4883
ApoB (g/L)			0.3306
NEFA (mmol/L)			0.0026
Creatinine (μmol/L)			0.0959
Uric acid (μmol/L)			0.4389
Glucose (mmol/L)			0.1354
CKMB (ng/ml)			0.0442
MYO (ng/ml)			0.516
HsTNT (ng/L)			0.0183
NT-proBNP (ng/L)			<0.0001
Echocardiographic parameters
LVEF (%)			<0.0001
LVFS (%)			<0.0001
LVDd (mm)			<0.0001
LVDs (mm)			<0.0001
IVST (mm)			<0.0001
LVPWd (mm)			<0.0001
ESV (ml)			<0.0001
EDV (ml)			<0.0001
NYHA class
II (, %)	0	10, 20%
III (, %)	0	29, 58%
IV (, %)	0	11, 22%
HF type
HFrEF (, %)	0	12, 24%
HFmrEF (, %)	0	29, 58%
HFpEF (, %)	0	9, 18%
Etiology
Hypertension (, %)	0	14, 28%
Myocardial infarction (, %)	0	11, 22%
Diabetes mellitus (, %)	0	13, 26%
Coronary artery disease (, %)	0	9, 18%
Valvular heart disease (, %)	0	3, 6%

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; LDH: lactate dehydrogenase; CK: creatine kinase; CHO: cholesterol; TG: total triglyceride; LDL: low-density lipoprotein; HDL: high-density lipoprotein; ApoA: apolipoprotein A; ApoB: apolipoprotein B; NEFA: nonestesterified fatty acid; CKMB: creatine kinase MB; MYO: myoglobin; hsTNT: high sensitivity troponin T; NT-proBNP: N-terminal pro-B type natriuretic peptide; LVEF: left ventricular ejection fraction; LVFS: left ventricular fractional shortening; LVDd: left ventricular diameter at end-diastole. LVDs: left ventricular diameter at end-systole; IVST: interventricular septum thickness; LVPWd: left ventricular posterior wall diameter; ESV: end-systolic volume; EDV: end-diastolic volume; NYHA: New York Heart Association Class; HFrEF: HF with reduced EF; HFmrEF: HF with mildly reduced EF; HFpEF: HF with preserved EF.