Research Article
Actin-Binding LIM 1 (ABLIM1) Inhibits Glioblastoma Progression and Serves as a Novel Prognostic Biomarker
Table 2
Cancer-specific survival analyses of GBM patients.
| Variables | Cases | Univariate analysis | Multivariate analysis | () | 3-Y CSS rate | value | HR (95% CI) | value |
| Age | | | | | | <62 yrs | 51 | 53.7% | | Reference | | ≥62 yrs | 53 | 11.8% | <0.001 | 2.7 (1.6-4.6) | <0.001 | Sex | | | | | | Female | 51 | 33.6% | | | | Male | 53 | 34.4% | 0.512 | | | Tumor size | | | | | | <4.0 cm | 53 | 44.5% | | Reference | | ≥4.0 cm | 51 | 24.0% | 0.031 | 1.1 (0.6-1.8) | 0.812 | Resection pattern | | | | | | Local resection | 55 | 32.9% | | | | Radical resection | 20 | 35.9% | | | | Lobectomy | 29 | 35.9% | 0.585 | | | Chemotherapy | | | | | | No or unknown | 85 | 41.8% | | | | Yes | 19 | 6.7% | 0.204 | | | ABLIM1 level | | | | | | Low | 56 | 12.4% | | Reference | | High | 48 | 54.7% | <0.001 | 0.3 (0.2-0.6) | <0.001 |
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by log-rank test. . Abbreviations: ABLIM1; actin-binding LIM protein 1; CI: confidence interval; CSS: cancer-specific survival; GBM: glioblastoma; HR: hazard ratio. |