Research Article

Loss of WNK1 Suppressed the Malignant Behaviors of Hepatocellular Carcinoma Cells by Promoting Autophagy and Activating AMPK Pathway

Figure 3

Loss of WNK1 promoted autophagy and AMPK pathway. (a, b) Loss of WNK1 increased the protein patterns of Beclin 1 and LC3 II, and reduced P62 level. (c, d) Immunofluorescence staining was used to detect LC3 II immunoreactivity. (e, f) Loss of WNK1 increased the protein patterns of p-AMPK in Huh7 and Hep3B cells. vs. si-con.
(a)
(b)
(c)
(d)
(e)
(f)