Research Article

Predictive Value of Heart-Type Fatty Acid-Binding Protein for Mortality Risk in Critically Ill Patients

Table 1

Comparison of patient baseline data.

Nonsurvivor group ()Survivor group ()

Gender (male/female)33/1362/420.107
Age (years)0.001
Underlying disease
 Diabetes (yes/no)17/2942/620.721
 Hypertension (yes/no)14/3231/730.938
 Coronary heart disease (yes/no)16/3028/760.338
Main diagnosis0.577
 Respiratory system23 (34.0%)45 (66.0%)
 Cardiovascular system diseases10 (24.4%)31 (75.6%)
 Other13 (31.7%)28 (68.3%)
APACHE II0.001
SOFA5.0 (3.8, 7.3)2.0 (1.0, 4.0)0.001
GCS13.5 (11.8, 15.0)15.0 (15.0, 15.0)0.001
WBC (109/l)0.491
CRP (mg/l)0.717
HB (g/l)0.925
PLT (109/l)0.656
Scr (umol/l)99.7 (68.6, 224.2)74.7 (55.9, 94.8)0.001
LAC (mmol/l)2.3 (1.4, 3.4)1.2 (0.8, 2.0)0.001
PCT (ng/ml)0.14 (0.05, 1.33)0.08 (0.02, 0.37)0.051
H-FABP (ng/ml)6.9 (3.9, 33.0)3.6 (2.0, 6.6)0.001
cTNI (ng/ml)0.06 (0.04, 0.59)0.05 (0.03, 0.27)0.139
IL-6 (pg/ml)51.6 (14.7, 139.3)19.4 (5.3, 64.7)0.001
D-dimer (mg/l)1.9 (1.00, 11.8)0.9 (0.4, 3.7)0.001

aAPACHE II: acute physiology and chronic health evaluation II; SOFA: sequential organ failure assessment score; GCS: Glasgow coma scale; H-FABP: heart-type fatty acid-binding protein; PCT: procalcitonin; cTNI: cardiac troponin I; IL-6: interleukin 6; LAC: lactate; Scr: serum creatinine; CRP: C-reactive protein; HB: hemoglobin. The differences were statistically significant when .