Transcription Factors Leading to High Expression of Neuropeptide L1CAM in Brain Metastases from Lung Adenocarcinoma and Clinical Prognostic Analysis

Figure 1

Functional features of L1CAM in LUAD. Survival curves of high and low L1CAM expressions in relation to LUAD overall survival (OS) (a), disease-specific survival (DSS) (b), and progression-free interval (PFI) (c); enrichment analysis associated with differential expression of L1CAM (d). Lollipop plot of L1CAM expression in relation to the degree of immune cell infiltration (e). Boxplot of differential expression of L1CAM in different M stages (f). Receiver operating characteristic curves for assessing the predictive power of L1CAM expression on survival (, 95% CI 0.623-0.695) (g). Boxplot showing the relationships between high and low L1CAM expressions, T cell enrichment score, and StromalScore (h, i). GSEA analysis of the enriched pathway associated with L1CAM expression (j).

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