Research Article
Nonalcoholic Fatty Liver Disease-Associated Liver Fibrosis Is Linked with the Severity of Coronary Artery Disease Mediated by Systemic Inflammation
Table 3
Binary and ordinal regression analysis of the risk for Gensini score in subjects with NAFLD according to fibrosis markers.
| Gensini score | Unadjusted | Adjusted† | OR (95% CI) | value | OR (95% CI) | value |
| 0 vs. >0 | | Reference | | Reference | | | 6.68 (3.19-14.00) | <0.001 | 5.67 (2.59-12.38) | <0.001 | | Reference | | Reference | | | 15.30 (3.58-65.42) | <0.001 | 14.81 (3.24-67.60) | <0.001 | ≤9 vs. >9 | | Reference | | Reference | | | 6.34 (3.34-12.03) | <0.001 | 5.72 (2.91-11.26) | <0.001 | | Reference | | Reference | | | 16.23 (4.80-54.85) | <0.001 | 15.51 (4.38-54.88) | <0.001 | <48 vs. ≥48 | | Reference | | Reference | | | 9.06 (4.83-17.02) | <0.001 | 8.65 (4.37-17.14) | <0.001 | | Reference | | Reference | | | 12.69 (5.52-29.16) | <0.001 | 12.00 (4.86-29.61) | <0.001 | 0 vs. 0-9 vs. 9-48 vs. ≥48 | | Reference | | Reference | | | 3.33 (2.42-4.60) | <0.001 | 2.87 (2.05-4.00) | <0.001 | | Reference | | Reference | | | 4.65 (2.92-7.43) | <0.001 | 4.08 (2.52-6.62) | <0.001 |
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NLR: neutrophil-to-lymphocyte ratio. , non-CAD; , mild coronary artery stenosis; , moderate coronary artery stenosis; , severe coronary artery stenosis. †Adjusted: adjusted for gender, age, smoking, hypertension, DM, triglyceride, HDL, and LDL. |