Research Article

Nonalcoholic Fatty Liver Disease-Associated Liver Fibrosis Is Linked with the Severity of Coronary Artery Disease Mediated by Systemic Inflammation

Table 3

Binary and ordinal regression analysis of the risk for Gensini score in subjects with NAFLD according to fibrosis markers.

Gensini scoreUnadjustedAdjusted†
OR (95% CI) valueOR (95% CI) value

0 vs. >0
ReferenceReference
6.68 (3.19-14.00)<0.0015.67 (2.59-12.38)<0.001
ReferenceReference
15.30 (3.58-65.42)<0.00114.81 (3.24-67.60)<0.001
≤9 vs. >9
ReferenceReference
6.34 (3.34-12.03)<0.0015.72 (2.91-11.26)<0.001
ReferenceReference
16.23 (4.80-54.85)<0.00115.51 (4.38-54.88)<0.001
<48 vs. ≥48
ReferenceReference
9.06 (4.83-17.02)<0.0018.65 (4.37-17.14)<0.001
ReferenceReference
12.69 (5.52-29.16)<0.00112.00 (4.86-29.61)<0.001
0 vs. 0-9 vs. 9-48 vs. ≥48
ReferenceReference
3.33 (2.42-4.60)<0.0012.87 (2.05-4.00)<0.001
ReferenceReference
4.65 (2.92-7.43)<0.0014.08 (2.52-6.62)<0.001

NLR: neutrophil-to-lymphocyte ratio. , non-CAD; , mild coronary artery stenosis; , moderate coronary artery stenosis; , severe coronary artery stenosis. Adjusted: adjusted for gender, age, smoking, hypertension, DM, triglyceride, HDL, and LDL.