Research Article
Nonalcoholic Fatty Liver Disease-Associated Liver Fibrosis Is Linked with the Severity of Coronary Artery Disease Mediated by Systemic Inflammation
Table 2
Association between fibrosis markers, inflammation markers, and CAD in logistic regression models.
| | Factors | Unadjusted | Adjusted† | | OR (95% CI) | value | OR (95% CI) | value |
| | Fibrosis markers | | | Reference | — | Reference | — | | | 6.68 (3.19-14.00) | <0.001 | 5.67 (2.59-12.38) | <0.001 | | | Reference | — | Reference | — | | | 15.30 (3.58-65.42) | <0.001 | 14.81 (3.24-67.60) | 0.001 | | Inflammation markers | | Neutrophil (109/L) | 1.35 (1.23-1.50) | <0.001 | 1.35 (1.21-1.50) | <0.001 | | Lymphocyte (109/L) | 0.90 (0.71-1.14) | 0.369 | 0.89 (0.69-1.157) | 0.389 | | Monocyte (109/L) | 6.32 (2.48-16.12) | <0.001 | 1.75 (0.62-4.99) | 0.293 | | NLR | 1.20 (1.10-1.32) | <0.001 | 1.18 (1.08-1.30) | <0.001 |
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NLR: neutrophil-to-lymphocyte ratio. †Adjusted: adjusted for gender, age, smoking, hypertension, DM, triglyceride, HDL, and LDL.
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