The Combination of CA125 and NSE Is Useful for Predicting Liver Metastasis of Lung Cancer

Table 5

The cutoff value, sensitivity, specificity, and AUC of CA125, NSE, and CA125+NSE in detecting the LM in metastatic lung cancer.

Factor	Cutoff value	Sensitivity	Specificity	AUC	value
CA125	53.0 U/mL	45.3%	72.1%	0.57	0.001
NSE	23.4 μg/L	43%	72.9%	0.59	<0.001
CA125+NSE		51.2%	72.6%	0.64	<0.001

Note: the sensitivity and specificity were calculated at the point of Youden’s index. indicates statistical significance. Abbreviations: AUC: area under the curve; CA: carbohydrate antigen; NSE: neuron-specific enolase; LM: liver metastasis.