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Disease Markers
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2020
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Article
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Tab 2
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Research Article
Analysis of Molecular Pretreated Tumor Profiles as Predictive Biomarkers of Therapeutic Response and Survival Outcomes after Neoadjuvant Therapy for Rectal Cancer in Moroccan Population
Table 2
Type of RAS mutation detected in our study.
Gene
Exon
Codon change
Nucleotide change
Protein change
N
KRAS
2
12
GGT-GTT
p.G12V
4/57
2
12
GGT-GAT
p.G12D
7/57
2
12
GGT-TGT
p.G12C
3/57
2
13
GGC-GGA
p.G13D
2/57
4
146
GCA-ACA
p.A146T
2/57
4
146
GCA-CCA
p.A146V
2/57
NRAS
2
12
GGT-GAT
p.G12D
1/47
3
61
GAA-GTA
p.Q61L
1/57