Analysis of Molecular Pretreated Tumor Profiles as Predictive Biomarkers of Therapeutic Response and Survival Outcomes after Neoadjuvant Therapy for Rectal Cancer in Moroccan Population
Table 1
Clinicopathological and molecular characteristics of the study.
Patients ( (%))
Demographic characteristics
Median age, years
56 (28-81)
Gender
Female
25 (43.9)
Male
32 (56.1)
Age
<50
23 (40.4)
≥50
34 (59.6)
Clinicopathological characteristics
Location of tumor
High
5 (8.8)
Middle
26 (45.6)
Low
26 (45.6)
Type of neoadjuvant treatment
Chemoradiotherapy
39 (68.4)
Radiotherapy
18 (31.6)
Surgical procedure
Abdominoperineal excision
10 (17.5)
Anterior resection
47 (82.5)
R0/R1 status
R0
52 (91.2)
R1
5 (8.8)
Histologic type
Adenocarcinoma
54 (94.7)
Mucinous carcinoma/signet ring carcinoma
3 (5.3)
Degrees of differentiation
Well
29 (50.9)
Moderate
25 (43.9)
Poor/undifferentiated
3 (5.3)
Therapeutic response according to the percentage of tumor regression