Serum Soluble CD89-IgA Complexes Are Elevated in IgA Nephropathy without Immunosuppressant History
Table 1
Clinical and laboratory findings of IgAN patients and healthy controls.
IgAN ()
Healthy controls ()
value
Age (years)
0.388
Gender (M/F)
14/16
13/17
0.795
IgA (mg/mL)
3.14 (2.40, 4.08)
2.12 (1.46, 2.82)
0.002
sCD89-IgA (OD405nm)
0.401 (0.290, 0.556)
0.266 (0.217, 0.351)
<0.001
Creatinine (μmol/L)
72 (56, 85)
eGFR (mL/min/1.73m2)
104.6 (82.6, 118.9)
Cys-C (mg/dL)
0.91 (0.76, 1.11)
Albumin (g/L)
hsCRP(mg/L)
0.64 (0.40, 1.31)
Proteinuria (g/24 h)
1.00 (0.51, 3.02)
U-RBC (-/1+/2+/3+)
2/5/4/18
Pathology (Oxford classification)a
M0/M1
0/24
E0/E1
8/16
S0/S1
8/16
T0/T1/T2
20/2/2
C0/C1/C2
2/19/3
RASI (yes/no)
20/10
aRenal histological grading was obtained in 24 patients who underwent biopsy in Peking Union Medical College Hospital. RASI: renin angiotensin system inhibitor; F: female; M: male; Cys-C: Cystatin C; U-RBC: urinary red blood cell.