Research Article

Serum Soluble CD89-IgA Complexes Are Elevated in IgA Nephropathy without Immunosuppressant History

Table 1

Clinical and laboratory findings of IgAN patients and healthy controls.

IgAN
()
Healthy controls
()
value

Age (years)0.388
Gender (M/F)14/1613/170.795
IgA (mg/mL)3.14 (2.40, 4.08)2.12 (1.46, 2.82)0.002
sCD89-IgA (OD405nm)0.401 (0.290, 0.556)0.266 (0.217, 0.351)<0.001
Creatinine (μmol/L)72 (56, 85)
eGFR (mL/min/1.73m2)104.6 (82.6, 118.9)
Cys-C (mg/dL)0.91 (0.76, 1.11)
Albumin (g/L)
hsCRP(mg/L)0.64 (0.40, 1.31)
Proteinuria (g/24 h)1.00 (0.51, 3.02)
U-RBC (-/1+/2+/3+)2/5/4/18
Pathology (Oxford classification)a
 M0/M10/24
 E0/E18/16
 S0/S18/16
 T0/T1/T220/2/2
 C0/C1/C22/19/3
RASI (yes/no)20/10

aRenal histological grading was obtained in 24 patients who underwent biopsy in Peking Union Medical College Hospital. RASI: renin angiotensin system inhibitor; F: female; M: male; Cys-C: Cystatin C; U-RBC: urinary red blood cell.