Research Article

Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Table 3

Relationship between clinicopathological variables and FEN1 expression level in TCGA database.

CharacteristicsFEN1
LowHigh value

GenderMale123 (54.9%)101 (45.1%)0.006
Female40 (38.5%)64 (61.5%)

Age<Median76 (47.2%)85 (52.8%)0.376
≥Median87 (52.1%)80 (47.9%)

RaceWhite90 (56.6%)69 (43.4%)0.015
Others73 (43.2%)96 (56.8%)

TNM stageStage I/II136 (55.5%)109 (44.5%)<0.001
Stage III/IV27 (32.5%)56 (67.5%)

Histologic gradeGrade I/II117 (58.2%)84 (41.8%)<0.001
Grade III/IV46 (36.2%)81 (63.8%)

AFPLow99 (63.1%)58 (36.9%)<0.001
High64 (37.4%)107 (62.6%)