Research Article

Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Table 1

The relationship of FEN1 expression in HCC with clinicopathological characteristics.

CharacteristicsFEN1
LowHigh value

SexFemale136 (51.9%)126 (48.1%)0.715
Male37 (49.3%)38 (50.7%)

Age<5065 (52%)60 (48%)0.851
≥50108 (50.9%)104 (49.1%)

Liver cirrhosisPresent160 (51.3%)152 (48.7%)0.945
Absent13 (52%)12 (48%)

AFP<2082 (50%)82 (50%)0.633
≥2091 (52.6%)82 (47.4%)

Tumor multiplicityMultiple43 (54.4%)36 (45.6%)0.529
Single130 (50.4%)128 (49.6%)

Pathologic TNM stageI/II168 (63.4%)97 (36.6%)<0.001
III/IV17 (23.61%)55 (76.39%)