Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Figure 2

FEN1 mRNA is significantly upregulated in HCC tissues. (a-e) The correlation of FEN1 expression with the TNM stage and histologic grade in TCGA and four GEO databases. (f) FEN1 mRNA expression in HCC tissues and paired nontumor tissues of TCGA and GEO databases. (g-h) The correlation of FEN1 expression with MKI67 and PCNA. FEN1: flap endonuclease 1; HCC: hepatocellular carcinoma; TMA: tissue microarrays; GEO: Gene Expression Omnibus; TCGA: The Cancer Genome Atlas; GSEA: gene set enrichment analysis; PCNA: proliferating cell nuclear antigen.

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