Potential Novel Biomarkers of Obstructive Nephropathy in Children with Hydronephrosis

Figure 8

ROC analysis for the urinary KIM-1/Cr ratio in the detection of obstructive nephropathy (ON). (a) Patients with obstructive nephropathy (ON) vs. controls. AUC of 0.653, an optimal cut-off value of 0.084 ng/mg Cr, sensitivity of 55.6%, specificity of 69.6%. (b) Patients with obstructive nephropathy (ON) vs. patients with hydronephrosis without obstructive nephropathy (HN without ON). AUC of 0.487, an optimal cut-off value of 0.119 ng/mg Cr, sensitivity of 88.9%, specificity of 16.7%.

(a)

(b)