Potential Novel Biomarkers of Obstructive Nephropathy in Children with Hydronephrosis

Figure 7

ROC analysis for the urinary NGAL/Cr ratio in the detection of obstructive nephropathy (ON). (a) Patients with obstructive nephropathy (ON) vs. controls. AUC of 0.663, an optimal cut-off value of 0.091 ng/mg Cr, sensitivity of 39.3%, specificity of 58.3%. (b) Patients with obstructive nephropathy (ON) vs. patients with hydronephrosis without obstructive nephropathy (HN without ON). AUC of 0.805, an optimal cut-off value of 0.079 ng/mg Cr, sensitivity of 78.6%, specificity of 58.3%.

(a)

(b)