Research Article

Potential Novel Biomarkers of Obstructive Nephropathy in Children with Hydronephrosis

Figure 5

ROC analysis for the urinary pi-GST/Cr ratio in the detection of obstructive nephropathy (ON). (a) Patients with obstructive nephropathy (ON) vs. controls. AUC of 0.3, an optimal cut-off value of 0.082 ng/mg Cr, sensitivity of 92.3%, specificity of <1%. (b) Patients with obstructive nephropathy (ON) vs. patients with hydronephrosis without obstructive nephropathy (HN without ON). AUC of 0.574, an optimal cut-off value of 0.103 ng/mg Cr, sensitivity of 92.3%, specificity of 7.7%.
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