Potential Novel Biomarkers of Obstructive Nephropathy in Children with Hydronephrosis

Figure 4

ROC analysis for the urinary alpha-GST/Cr ratio in the detection of obstructive nephropathy (ON). (a) Patients with obstructive nephropathy (ON) vs. controls. AUC of 0.902, an optimal cut-off value of 0.046 ng/mg Cr, sensitivity of 81.8%, specificity of 84.6%. (b) Patients with obstructive nephropathy (ON) vs. patients with hydronephrosis without obstructive nephropathy (HN without ON). AUC of 0.750, an optimal cut-off value of 0.098 ng/mg Cr, sensitivity of 84.6%, specificity of 69.2%.

(a)

(b)