Research Article
Identification of Factors for the Preoperative Prediction of Tumour Subtype and Prognosis in Patients with T1 Lung Adenocarcinoma
Table 2
Correlation of the resected lung adenocarcinoma classification
with clinical characteristics.
| Variable | Category | AIS and MIA
| IAC
| P value |
| Sex | Male | 15 (36.6) | 23 (50.0) | 0.279 | Female | 26 (63.4) | 23 (50.0) |
| Median age (years) | | | | < |
| Smoking | Always smoked | 33 (80.5) | 33 (71.7) | 0.453 | Never smoked | 8 (19.5) | 13 (28.3) |
| Radiological finding | Pure GGO | 18 (43.9) | 1 (2.2) | < | Mixed GGO | 23 (56.1) | 28 (60.9) | Pure solid nodule | 0 | 17 (36.9) |
| CEA [IQR (median)] (ng/mL) | | 1.17–2.32 (1.78) | 1.48–4.31 (2.30) | |
| Serum miR-183 [IQR (median)] | | 0.232–1.63 (0.790) | 0.684–4.33 (1.325) | |
| Tumour size | ≤10 mm | 36 (87.8) | 6 (13.0) | < | >10 to ≤20 mm | 4 (9.8) | 26 (56.5) | >21 to ≤30 mm | 1 (2.4) | 14 (30.5) |
| Lymph node metastasis | Absent | 41 (100.0) | 42 (91.3) | 0.119 | Present | 0 | 4 (8.7) |
| Visceral pleural invasion | Absent | 41 (100.0) | 37 (80.4) | | Present | 0 | 9 (19.6) |
| Pathological stage | 0/IA | 40 (97.6) | 30 (65.2) | < | IB/IIA/IIB/IIIA | 1 (2.4) | 16 (34.8) |
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significant p value CEA, carcinoembryonic antigen; GGO, ground-glass opacity; IQR, interquartile range; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IAC, invasive adenocarcinoma.
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