ACE Gene I/D Polymorphism and Obesity in 1,574 Patients with Type 2 Diabetes Mellitus

Table 6

Clinical and biochemical characteristics of 1,574 Chinese patients with type 2 diabetes relating to ACE I/D polymorphism.

	DD	ID	II	P	P	P
Patients ()	176	679	719	—	—	—
M : F	74 : 102	261 : 418	303 : 416	—	—	—
Age (years)				0.912	0.195	0.26
BMI (kg/m^2)				0.982	0.611	0.663
WHR				0.529	0.837	0.965
FPG (mmol/L)				0.494	0.165	0.352
(%)				0.452	0.406	0.66
TC (mmol/L)				0.947	0.710	0.772
TG (mmol/L)				0.736	0.222	0.254
LDL-C (mmol/L)				0.716	0.167	0.198
HDL-C (mmol/L)				0.825	0.132	0.18
SBP (mmHg)				0.144	0.066	0.041
DBP (mmHg)				0.801	0.123	0.226
MAP (mmHg)				0.517	0.066	0.078
PP (mmHg)				0.032	0.157	0.055

Data are shown as means ± SD. value is derived by analysis of variance (ANOVA).
P values compared DD genotype with II genotype.
P values compared ID genotype with II genotype.
P values compared DD + ID genotypes with II genotype.
BMI: body mass index; WHR: waist-to-hip ratio; FPG: fasting plasma glucose; : glycated hemoglobin; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; PP: pulse pressure.