Research Article

The Markers of Glutamate Metabolism in Peripheral Blood Mononuclear Cells and Neurological Complications in Lung Cancer Patients

Table 1

The content of glutamate and activities of GLS, GDH, and GAD in PBMC of lung cancer patients during chemotherapy. ; , and .

BaselineAfter 6-month chemotherapy

Glutamate (nmol/mg protein) median; minimum–maximum1.03
0–5543.42
253.5
0–41615.30

Glutaminase (mU/mg protein) median; minimum–maximum0.42
0–91.33
0.089
0–31.97

Glutamate dehydrogenase (mU/mg protein) median; minimum–maximum3.67
1.57–1594.61
15.99
4.08–3185.02

Glutamate decarboxylase (U/mg protein) median; minimum–maximum0.85
0–33.25
0.93
0–79.98