Disease Markers / 2015 / Article / Tab 4

Research Article

Identification of Differentially Expressed Genes Associated with Prognosis of B Acute Lymphoblastic Leukemia

Table 4

Survival analysis and OR values for differentially expressed genes between B-ALL relapsed patients and event-free cases.

Gene-time
(cutoff value)
Group±/eventsSurvival time
(mean, months)
Standard error95% CI valueOR95% CI value

FLT3-T1
(0.1719)
138/731.131.80327.6–34.70.012*3.731.3–10.720.024*
235/1625.0032.67919.7–30.3

IL2RA-T1
(1.173)
138/731.051.82927.5–34.60.012*3.731.3–10.720.024*
235/1624.712.74519.3–30.1

FLT3-T2
(−0.4638)
132/431.471.90127.7–35.20.004*6.051.8–20.360.005*
241/1925.192.39820.5–29.9

FLT3-T3
(−0.149)
135/534.831.92831.1–38.60.002*5.41.7–16.90.005*
238/1823.022.30918.5–27.6

DEFA1-T3
(3.041)
143/830.841.77527.4–34.30.006*4.381.5–12.50.01*
230/1524.132.82518.6–29.7

IL2RA-T1-children
(1.220)
125/332.762.15328.5–37.00.0624.030.98–16.60.088
230/1028.572.85723.0–34.2

FLT3-T2-children
(−0.475)
124/133.830.003*14.531.7–122.10.008*
231/1227.042.84421.5–32.6

FLT3-T3-adults
(−0.304)
19/324.874.12816.7–33.00.038*272.0–368.40.013*
29/711.441.0619.4–13.5

SORT1-T3-Adults
(5.007)
17/0<0.001*141.1–172.60.05
210/10111.1938.7–13.3

FLT3-T2-standard risk
(−0.464)
118/0<0.001*Undetermined<0.001*
216/822.513.62515.4–29.6

DEFA1-T3-high risk
(3.041)
126/527.712.78022.3–33.20.0814.01.02–15.720.089
228/1022.793.62715.7–29.9

Group 1 represents B-ALL cases with a log 2 of expression level ≤ cutoff value (for the indicated gene); in the group 2 those patients with their log 2 of expression level > cutoff for the indicated gene were included. value for survival curves differences. value for OR test. Event indicates relapse or death.
*Statistical significance.

You are browsing a BETA version of Hindawi.com. Click here to switch back to the original design.