Identification of Differentially Expressed Genes Associated with Prognosis of B Acute Lymphoblastic Leukemia

Table 3

Positive associations between gene expression level and relapse/death.

Classification of study population	Gene	Time 1			Time 2			Time 3
		Event- free group	Event group	value	Event-free group	Event group	value	Event- free group	Event group	value
All the ALL cases	FLT3	−0.049	0.434	0.022^*	−0.598	−0.075	0.028^*	−0.242	0.023	0.02^*
	IL2RA	1.164	1.493	0.038^*	—	—	—	—	—	—
	DEFA1	—	—	—	—	—	—	1.99	4.012	0.01^*
Children	FLT3	—	—	—	−0.602	0.025	0.044^*	—	—	—
	IL2RA	1.193	1.558	0.038^*	—	—	—	—	—	—
Adults	FLT3	—	—	—	—	—	—	−0.49	0.03	0.046^*
	SORT1	—	—	—	—	—	—	3.84	5.34	0.039^*
Standard risk	FLT3	—	—	—	−0.707	−0.025	0.008^*	—	—	—
High risk	DEFA1	—	—	—	—	—	—	2.33	4.62	0.018^*

Statistically significant.