Serum Cytokine of IL-10 and IL-12 in Chronic Liver Disease: The Immune and Inflammatory Response
Table 1
Clinical, biochemical, and virological characteristics of the studied group.
Chronic liver disease ( = 41)
NDC ( = 10)
HCC
LC
PCH
No (%)
15/41 (36.6%)
16/41 (39.0%)
10/41 (24.4%)
10/10 (100%)
Gender (M/F)
13/2
12/4
9/1
7/3
Age (years)
57.06 ± 12.58 (60.0)
46.06 ± 7.9 (45.0)
35.8 ± 5.2 (37.5)
35.6 ± 3.1 (35.5)
Albumin (g/dL)
4.22 ± 0.58 (4.3)
4.15 ± 0.467 (4.0)
4.5 ± 0.42 (4.6)
3.83 ± 0.29 (3.85)
T. protein (g/dL)
7.95 ± 0.603 (8.0)
7.6 ± 0.67 (7.8)
7.66 ± 0.49 (7.85)
7.22 ± 0.53 (7.15)
T. bilirubin (mg/dL)
1.69 ± 2.57 (1.2)
1.28 ± 1.54 (1.0)
0.99 ± 0.54 (0.9)
0.57 ± 0.21 (0.55)
AST (μ/mL)
92.8 ± 65.67 (67.0)
57.0 ± 26.6 (52.5)
34.8 ± 11.44 (30.5)
26.6 ± 5.5 (26.5)
ALT (μ/mL)
58.73 ± 36.86 (46.0)
49.0 ± 17.35 (49.0)
32.6 ± 14.8 (25.5)
27.7 ± 4.1 (27.5)
Proth. time (Sec)
14.3 ± 1.7 (14.0)
13.58 ± 4.66 (14.6)
13.2 ± 4.77 (13.3)
6.04 ± 0.568 (6.1)
Proth. conc. (%)
72.26 ± 13.78 (70.0)
70.375 ± 12.99 (69.0)
73.1 ± 19.0 (78.0)
258.4 ± 14.06 (256.0)
HCV infection
Positive
11/15 (73.3%)
14/16 (87.5%)
8/10 (80%)
0/10 (0.0%)
Negative
4/15 (26.7%)
2/16 (12.5%)
2/10 (20%)
10/10 (100%)
Tumor site
Right lobe
7/15 (46.7%)
Left lobe
8/15 (53.3%)
HCC grade
Grade I
2/15 (13.3%)
Grade II
4/15 (26.7%)
Grade III
9/15 (60.0%)
Child score
A
3/15 (20.0%)
B
6/15 (40.0%)
C
6/15 (40.0%)
Data expressed as mean ± SD (median). Hepatocellular carcinoma (HCC), liver cirrhosis (LC), precirrhotic hepatitis (PCH), nondisease control (NDC). Significant difference was detected between PCH and LC () and HCC (). Significant difference was detected between PCH and LC () and HCC ().
