Reduced Histone H3 Acetylation in CD4⁺ T Lymphocytes: Potential Mechanism of Latent Autoimmune Diabetes in Adults

Figure 2

Global H3/H4 acetylation status in CD4⁺ T lymphocytes. (a) Global H3/H4 acetylation status in CD4⁺ T lymphocytes from patients with LADA () and healthy controls (), , LADA patients versus healthy controls. (b) Global H3/H4 acetylation status in CD4⁺ T lymphocytes from patients with LADA, , LADA patients with HbA1c > 7% () versus LADA patients with patients HbA1c < 7% (). (c) Global H3/H4 acetylation status in CD4⁺ T lymphocytes from patients with LADA, , LADA patients with complications (LADAc, ) versus LADA patients without complications (LADAnc, ). (d) Global H3/H4 acetylation status in CD4⁺ T lymphocytes from patients with LADA, , high GADA titer () versus low GADA titer ().

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