Serum YKL-40 Levels and Chitotriosidase Activity in Patients with Beta-Thalassemia Major

Table 1

Clinical and serological parameter in 69 thalassemic patients and healthy controls.

Parameters	Thalassemic patients	Reference values	Healthy controls	Spearman 𝑃 test
Age (years)	33	—	38	𝑃=0.60
	(15–69)		(27–47)
Sex M/F	34/35	—	10/11	—
AST U/L	23	Up to 37	17	𝑃=0.63
	(9–156)		(8–34)
ALT U/L	26	Up to 78	27	𝑃=0.54
	(8–142)		(17–54)
GGT U/L	21	15–85	20	𝑃=0.46
	(5–153)		(9–82)
LDH U/L	325	0–248	170.5	𝑃=0.84
	(166–1082)		(123–208)
Total proteins gr/dL	7.2	6.4–8.3	7.25	𝑃=0.07
	(6.5–7.25)		(6.5–8.25)
Albumin/globulin ratio	1.56	1.10–2.40	1.55	𝑃=0.95
	(0.93–1.28)		(1.22–1.87)
Ferritin ng/mL	1250	F 8–252	157	𝑃=0.52
	(89–9110)	M 26–388	(34–314)
SQUID	1296	—	—	—
	(254–3379)
MR	5.61	—	—	—
	(0.38–43)
Chitotriosidase nmol/mL/hr	84.38	—	44	𝑃=0.005
	(1.03–519)		(0.6–73)
YKL-40 μg/L	37.6	—	29.18	𝑃=0.27
	(14–117.32)		(17.5–111.4)