CLCA2 as a Novel Immunohistochemical Marker for Differential Diagnosis of Squamous Cell Carcinoma from Adenocarcinoma of the Lung

Figure 3

CLCA2 protein expression level in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of the lung. (a) The staining intensity of the cancer cells in immunohistochemical analysis using anti-CLCA2 antibody. Examples for intensity levels of the values of 0, 1+, 2+, and 3+ are shown. Scale bar = 10 μm. (b) Box-plot analysis was performed for the results of CLCA2 immunohistochemistry in cases with ADC () and cases with SCC of the lung (). Median values are shown. A statistically significant difference in the CLCA2 expression level was detected between the two groups (, Mann-Whitney test).

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