Cardiovascular diseases are becoming increasingly frequent and associated with a high incidence of cardiovascular events, disability, and death. In many chronic conditions, the inflammatory response continues and leads to significant tissue/organ damage. Recently, increasing evidence shows that cardiovascular disease is closely associated with abnormal inflammatory responses, including rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, gout, diabetes, and metabolic syndrome. Although the importance of inflammation in cardiovascular diseases has been revealed in recent years, its mechanism remains elusive. Knowledge of the mechanism of inflammation regulation will lead to significant clinical benefit for patients.

In this special issue, we invite researchers to contribute original research articles, as well as review articles, that will stimulate the continuing efforts to understand the regulation of inflammation in the pathology and the treatment of cardiovascular diseases. We are particularly interested in articles describing novel mechanisms, new treatment strategies, clinical studies, advances in genetics, and molecular diagnostics.

Potential topics include but are not limited to the following:

• Mechanisms regulating inflammation in cardiovascular diseases
• Role of innate immunity in cardiovascular diseases
• Role of adaptive immunity in cardiovascular diseases
• Inflammatory cytokines in cardiovascular diseases
• The role of gut microbiota in chronic inflammation and cardiovascular diseases
• The role of extracellular matrix in chronic Inflammation and cardiovascular diseases
• Inflammatory markers in the diagnosis of cardiovascular diseases