Research Article

Serum VEGF: Diagnostic Value of Acute Coronary Syndrome from Stable Angina Pectoris and Prognostic Value of Coronary Artery Disease

Table 1

Baseline characteristics of study population.

Control (n = 48)CAD (n = 248) value

Age (years)61.15 ± 8.0261.54 ± 8.360.705
Sex (n, male)23 (47.9%)105 (42.3%)0.475
Hypertension (n, %)0 (0%)126 (73.3%)NS
Diabetes mellitus (n, %)0 (0%)53 (30.8%)NS
Smoking (n, %)0 (0%)89 (51.7%)NS
HbA1c (%)5.97 ± 0.686.35 ± 1.210.009
CK-MB (U/L)9.2 (7.7, 11.4)11.0 (9.0, 13.4)0.003
TnI0.003 (0.001, 0.008)0.007 (0.003, 0.023)<0.001
TC4.73 (3.98, 5.38)4.69 (4.09, 5.48)0.860
TG1.21 (1.00, 1.67)1.51 (1.16, 2.04)0.011
HDL-c1.35 (1.13, 1.60)1.17 (1.02, 1.35)0.002
LDL-c (mg/dL)3.05 ± 0.632.88 ± 0.680.086
Cr (mg/dL)70.06 ± 5.7571.95 ± 9.270.066
LVEF (%)60.33 ± 3.6159.14 ± 5.420.145
Gensini scoreNS38 (17, 74)NS
PCI (n, %)NS100 (40.3%)NS
VEGF (pg/mL)160.93 (121.09, 303.26)645.57 (319.48, 901.14)<0.001

Date are expressed as mean ± SD (standard deviation), median (interquartile range), and absolute number (percentage). value for comparison between the CAD and the control group. . HbA1c: hemoglobin A1c; CK-MB: creatine kinase-MB; TnI: troponin I; TC: total cholesterol; TG: triglyceride; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; Cr = creatinine; LVEF: left ventricular ejection fraction; PCI: percutaneous coronary intervention; VEGF = vascular endothelial growth factor.