Similarities and Differences between the Pathogenesis and Pathophysiology of Diastolic and Systolic Heart Failure
Figure 1
(a) The end-systolic pressure-volume relationship is the same as a normal heart in diastolic heart failure, but the end-diastolic pressure-volume relationship shifts upwards. As a result, left ventricular end-diastolic pressure rises. (b) In pathologies with diastolic dysfunction, when an abrupt increase in blood pressure occurs, the pressure-volume loop shifts to the upper right without decrease in . Therefore, pulmonary congestion is induced as a result of the significant increase in left ventricular end-diastolic pressure. LV: left ventricular.